The welfare of the students in the University is considered crucial to the well-being of the entire University community. The University has an office of the Director of Students Welfare Services. The Director of Students works in conjunction with the Dean of Students in all matters affecting students' life and welfare. Students are encouraged to participate in as many activities as possible in order to make their non-academic life fully worthwhile.

In conjunction with relevant organs of the University, the office of the Director of Students' Welfare Services also coordinates activities that affect student's health, accommodation and catering, sports, career, and placement services including activities of Student Organization of Maseno University (SOMU), student clubs, societies, and associations. In addition, the office co-ordinates student loans, bursaries, work-study, and student Welfare activity programmes among others.

It serves as a link between the University administration and the student fraternity. The office liaises with the general public on matters affecting individual and groups of students' participation in community services.